We recommend using it in conjunction with Liquitox Step 1 and 2 and Age Defying Fountain of Youth Vital C Serum or the new Immaculate Cream. These all-natural formulas are highly effective and contain active botanicals that will greatly benefit the skin. For the best results, apply the serum and cream to the skin before using it, which allows for deeper penetration of your serum and greater results. There are two ends on the roller; the large roller is meant for your forehead, cheeks, and neck while the small end is for under the eyes and around the mouth. Don’t forget to extend the serum down to your neck area. Always focus on using upward and outward lifting motions while you roll. This will give you an instant glow! Use gentle pressure. All you need to do is wipe it clean after you are done with it. Use a dry clean washcloth, and voila!